Two studies conducted at the Grenoble Institute of Neuroscience as part of Clarissa Baratin’s PhD research and published in Nature Communications show that our brain does not rely on exactly the same neural circuits to evaluate pleasant and unpleasant experiences, and that its activity immediately before a decision can influence our choices.
Doubting what we have seen, what we have done, or a decision we have just made: doubt is a prominent feature of obsessive-compulsive disorder (OCD). A study conducted at the Grenoble Institute of Neuroscience suggests that this doubt may not result from poorer visual perception, but could instead be linked to altered metacognition, the ability to evaluate one’s own perceptions.
A study conducted at the Grenoble Institute of Neuroscience shows, in a progressive macaque model of Parkinson’s disease, that activity in the subthalamic nucleus changes before the onset of motivational, cognitive and then motor impairments. These findings could pave the way for deep brain stimulation strategies better tailored to each patient’s symptoms.
In preclinical research on alcohol addiction, rats are often housed alone. A team from the Grenoble Institute of Neurosciences investigated whether they could be housed in pairs without compromising the validity of the experimental model. Their findings reveal a more complex picture than might be expected.
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Two studies conducted at the Grenoble Institute of Neuroscience as part of Clarissa Baratin’s PhD research and published in Nature Communications show that our brain does not rely on exactly the same neural circuits to evaluate pleasant and unpleasant experiences, and that its activity immediately before a decision can influence our choices.
Doubting what we have seen, what we have done, or a decision we have just made: doubt is a prominent feature of obsessive-compulsive disorder (OCD). A study conducted at the Grenoble Institute of Neuroscience suggests that this doubt may not result from poorer visual perception, but could instead be linked to altered metacognition, the ability to evaluate one’s own perceptions.
A study conducted at the Grenoble Institute of Neuroscience shows, in a progressive macaque model of Parkinson’s disease, that activity in the subthalamic nucleus changes before the onset of motivational, cognitive and then motor impairments. These findings could pave the way for deep brain stimulation strategies better tailored to each patient’s symptoms.
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De Schlichting E, Meng Y, Huang Y, Jones RM, Hynynen K, Hamani C, Abrahao A, Davidson B, Lipsman N.
Expert Rev Med Devices. 2025 Jul 11:1-9. doi: 10.1080/17434440.2025.2530765. - Characterizing early auditory deficits in schizophrenia using drift-diffusion modeling.
Dondé C, Pereira M, Nalborczyk L, Roux P, Faivre N, Brunelin J.
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