Alzheimer
Giving neurons a second youth: Leticia Peris's approach to combating Alzheimer's disease
On September 11, 2025
Awarded of the Alzheimer's Foundation's 2024 ‘Innovative Programmes’ call for projects, Leticia Peris, an Inserm researcher at GIN, is studying the combined effects of toxic amyloid and Tau proteins implicatedin Alzheimer's disease. Her ambition is to strengthen neural connections in order to preserve cognitive functions.
By successfully recording the activity of individual neurons in humans, neuroscientists have shown that certain subcortical structures play an important role in perceptual consciousness.
Alzheimer
Could the intestinal signature be an early biomarker for Alzheimer's disease?
On July 30, 2025
In a webinar recorded for Zeiss, Maxime Seignobos, a doctoral student at GIN, presents his research on the links between the brain, the intestine, and neurodegenerative disease. This work could lead to early, non-invasive diagnosis of Alzheimer's disease.
Eq I.Arnal et A.Andrieux
Neuronal protein MAP6d1 assembles the microtubule framework of primary cilia
On July 23, 2025
By studying the MAP6d1 protein, a team of researchers at GIN has made important discoveries in understanding the molecular mechanisms governing microtubule doublet formation and cilia physiology.
Events
News
Communiqué, Accolade/Award
Giving neurons a second youth: Leticia Peris's approach to combating Alzheimer's disease
On September 11, 2025
Awarded of the Alzheimer's Foundation's 2024 ‘Innovative Programmes’ call for projects, Leticia Peris, an Inserm researcher at GIN, is studying the combined effects of toxic amyloid and Tau proteins implicatedin Alzheimer's disease. Her ambition is to strengthen neural connections in order to preserve cognitive functions.
By successfully recording the activity of individual neurons in humans, neuroscientists have shown that certain subcortical structures play an important role in perceptual consciousness.
Communiqué, Lecture
Could the intestinal signature be an early biomarker for Alzheimer's disease?
On July 30, 2025
In a webinar recorded for Zeiss, Maxime Seignobos, a doctoral student at GIN, presents his research on the links between the brain, the intestine, and neurodegenerative disease. This work could lead to early, non-invasive diagnosis of Alzheimer's disease.
Latest publications
- Subcortical correlates of consciousness with human single neuron recordings
Michael Pereira, Nathan Faivre, Fosco Bernasconi, Nicholas Brandmeir , Jacob E Suffridge, Kaylee Tran, Shuo Wang , Victor Finomore, Peter Konrad , Ali Rezai, Olaf Blanke
Elife. 2025 May 22:13:RP95272. doi: 10.7554/eLife.95272. - The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules.
Dharshini Gopal, Juliette Wu, Julie Delaroche, Christophe Bosc, Manon De Andrade, Eric Denarier, Gregory Effantin, Annie Andrieux, Sylvie Gory-Fauré, Laurence Serre & Isabelle Arnal
Nature Communications, 2025, 16 (1), pp.6210. (10.1038/s41467-025-61679-0) - Relaxometry and contrast-free cerebral microvascular quantification using balanced steady-state free precession MR fingerprinting.
Coudert T, Delphin A, Barrier A, Legris L, Warnking JM, Lamalle L, Doneva M, Lemasson B, Barbier EL, Christen T.
Magn Reson Med. 2025 Jul;94(1):302-316. doi: 10.1002/mrm.30434. Epub 2025 Jan 17. - Mapping GABA+/Glx in experimental temporal lobe epilepsy using edited-MRSI at 9.4T
Alicia Plaindoux, Yann Le Fur, Clothilde Courivaud, Camille Beets, Loan Samalens, Julien Valette, Benjamin Lemasson, Emmanuel L. Barbier, Vasile Stupar, Florence Fauvelle
NeuroImage, Volume 315, 15 July 2025, 121274 - Toward an Automatic Classification of the Different Stages of Sleep: Exploring Patterns of Neural Activity in the Subthalamic Nucleus
Barbe N, Connolly M, Devergnas A, Torrès N, Hervault M, Bonis M, Billères M, Chabardes S, Piallat B.
Eur J Neurosci. 2025 Apr;61(7):e70107. doi: 10.1111/ejn.70107 - RyR1 Is Involved in the Control of Myogenesis
Tourel A, Reynaud-Dulaurier R, Brocard J, Fauré J, Marty I, Petiot A
Cells. 2025 Jan 21;14(3):158. doi: 10.3390/cells14030158
PMID: 39936950 Free PMC article - Unilateral and Bilateral Subthalamic Deep Brain Stimulation Differently Favour Apathy in Parkinson's Disease
Vachez YM, Bahout M, Magnard R, David PM, Carcenac C, Wilt M, Robert G, Savasta M, Carnicella S, Vérin M, Boulet S
Eur J Neurosci. 2025 Feb;61(4):e70019. doi: 10.1111/ejn.70019
PMID: 39962903 Free PMC article - Zona incerta: from Parkinson's disease to addiction
Wilt M, Magnard R, Carnicella S, Vachez YM
Front Neural Circuits. 2025 Feb 6;19:1537449. doi: 10.3389/fncir.2025.1537449. eCollection 2025
PMID: 39991498 Free PMC article. No abstract available.