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Researchers at the GIN provide a new understanding of the dynamic instability of microtubules.
GIN researchers have succeeded in proving that the thalamus is indeed involved in trial-and-error learning. Their findings have been published in the scientific journal Nature Communications.
Amyloid beta induces synaptic damage by reducing dynamic microtubule entry into dendritic spines
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Latest publications
- Human thalamic low-frequency oscillations correlate with expected value and outcomes during reinforcement learning
Collomb-Clerc A, Gueguen MCM, Minotti L, Kahane P, Navarro V, Bartolomei F, Carron R, Regis R, Chabardes S, Palminteri S and Bastin J .
Nat Commun 14, 6534 (2023) ; doi.org/10.1038/s41467-023-42380-6 - Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning
Hélène Vitet, Julie Bruyère, Hao Xu, Claire Séris, Jacques Brocard, Yah-Se Abada, Benoît Delatour, Chiara Scaramuzzino, Laurent Venance, Frédéric Saudou
eLife 12:e81011. ; 11 Juillet 2023 ; doi.org/10.7554/eLife.81011 - Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
Julia Schaeffer, Noemie Vilallongue, Charlotte Decourt, Beatrice Blot, Nacera El Bakdouri, Elise Plissonnier, Blandine Excoffier, Antoine Paccard, Jean-Jacques Diaz, Sandrine Humbert, Frederic Catez, Frederic Saudou, Homaira Nawabi‡, Stephane Belin‡
J Neuron. 12 juillet 2023 ; doi.org/10.1016/j.neuron.2023.06.005 - Altered parabrachial nucleus nociceptive processing may underlie central pain in Parkinson’s disease
Pautrat, A., Al Tannir, R., Pernet-Gallay, K. et al.
npj Parkinsons Dis. 9, 78 (2023). - The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems
Charlotte Decourt, Julia Schaeffer, Beatrice Blot, Antoine Paccard, Blandine Excoffier, Mario Pende, Homaira Nawabi, Stephane Belin.
PLoS Biol 21(4) (2023). - Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use.
Goutaudier, R., Joly, F., Mallet, D. et al.
Mol Psychiatry (2022). - Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system
Noémie Vilallongue, Julia Schaeffer, Anne-Marie Hesse, Céline Delpech, Béatrice Blot, Antoine Paccard, Elise Plissonnier, Blandine Excoffier, Yohann Couté, Stéphane Belin, Homaira Nawabi.
Nature Communications, 13 octobre 2022. - Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
Martínez-Hernández J, Parato J, Sharma A, Soleilhac JM, Qu X, Tein E, Sproul A, Andrieux A, Goldberg Y, Moutin MJ, Bartolini F, Peris L.
Front Cell Dev Biol. 2022;10:926914. eCollection 2022. PubMed PMID: 36092705; PubMed Central PMCID: PMC9459041. doi: 10.3389/fcell.2022.926914.