A major discovery made at GIN, which opens up new avenues for understanding the long-term side effects of this essential treatment.
Schizophrénie
Bipolar disorder: distinct brain activity even during stable mood states
On November 7, 2025
An international team of researchers has shown that the brains of people with bipolar disorder do not process emotional information in quite the same way as those of individuals without psychiatric disorders – including when their mood is stable and no clear symptoms are visible.
Conscience
How and when does the brain transform a fleeting image into conscious perception?
On October 24, 2025
An international team of researchers has recently demonstrated that our cortex accumulates the sensory information necessary for consciousness even when no response is required. These findings, published in Nature Communications, shed new light on the neural basis of perceptual consciousness.
A collaborative French-Swiss study reveals a previously unknown role for astrocytes in the brain's information processing. Published in the journal Cell, the research shows that these glial cells are capable of integrating signals from several neurons at once—a conceptual shift in our understanding of the brain.
Events
News
Communiqué
14 Doctorats et 6 Habilitations à diriger des recherches soutenus au GIN en 2025
On December 17, 2025
En 2025, 14 doctorantes et doctorantes ont obtenu le titre de Docteur après avoir préparé leur thèse dans les équipes du GIN.
L’équipe « Myologie cellulaire et Pathologies » dirigée par Isabelle Marty s’est une nouvelle fois mobilisée pour le Téléthon. Pour cette 4e édition au GIN, un stand gourmand tenu par ses membres a pris place dans le hall de l’institut, attirant tout au long de la journée personnels, chercheurs, étudiants et visiteurs souhaitant apporter leur soutien.
A major discovery made at GIN, which opens up new avenues for understanding the long-term side effects of this essential treatment.
Latest publications
- L-Dopa-modified microtubules lead to synapse instability in cultured neurons: possible implications in Parkinson’s disease therapy
Agustina Zorgniotti, Aditi Sharma, Sacnicte Ramirez-Rios, Chadni Sanyal, Martina Aleman, Yanina Ditamo, Marie-Jo Moutin, C. Gastón Bisig, Leticia Peris
J npj Parkinsons Dis. 11, 298 (2025). doi.org/10.1038/s41531-025-01143-4 - Event-related potential alterations in bipolar disorder subtypes and mood states: Insights from an emotional visual task
Ronen Sosnik, Antoine Bertrand, Muli Linder, Mircea Polosan
J Affect Disord. 2025 Dec 15;391:119970. doi: 10.1016/j.jad.2025.119970. Epub 2025 Jul 23. PMID: 40712679. - Event-related potential alterations in bipolar disorder subtypes and mood states: Insights from an emotional visual task
Ronen Sosnik, Antoine Bertrand, Muli Linder, Mircea Polosan
J Affect Disord. 2025 Dec 15;391:119970. doi: 10.1016/j.jad.2025.119970. Epub 2025 Jul 23. PMID: 40712679. - Cortical evidence accumulation for visual perception occurs irrespective of reports
François Stockart, Ramla Msheik, Alexis Robin, Lenka Jurkovičová, Dorian Goueytes, Martin Rouy, Radek Mareček, Dominique Hoffmann, Liad Mudrik, Robert Roman, Milan Brázdil, Lorella Minotti, Philippe Kahane, Michael Pereira*, Nathan Faivre*.
Nat Commun. 2025 Sep 26;16(1):8458. doi: 10.1038/s41467-025-63255-y.* contribution égale. - Magnetic resonance-guided ultrasound thalamotomy for essential tremor: a review.
De Schlichting E, Meng Y, Huang Y, Jones RM, Hynynen K, Hamani C, Abrahao A, Davidson B, Lipsman N.
Expert Rev Med Devices. 2025 Jul 11:1-9. doi: 10.1080/17434440.2025.2530765. - Characterizing early auditory deficits in schizophrenia using drift-diffusion modeling.
Dondé C, Pereira M, Nalborczyk L, Roux P, Faivre N, Brunelin J.
Schizophr Res. 2025 Jul 29;284:23-31. doi: 10.1016/j.schres.2025.07.024. Online ahead of print. PMID: 40737765 - Impaired effort allocation in schizophrenia
Blouzard E, Cignetti F, Meyniel F, Pouchon A, Polosan M, Bastin J, Dondé C.
Schizophr Res Cogn. 2025 Jul 15;42:100378. doi: 10.1016/j.scog.2025.100378. eCollection 2025 Dec. PMID: 40697646 Free PMC article. - Astrocytes functionally integrate multiple synapses via specialized leaflet domains.
Lucas Benoit, Ines Hristovska, Nicolas Liaudet, Pierre-Henri Jouneau, Arnold Fertin, Roberta de Ceglia, David Litvin, Maria Amalia Di Castro, Milica Jevtic, Ioannis Zalachoras, Toko Kikuchi, Ludovic Telley, Matteo Bergami, Yves Usson, Chihiro Hisatsune, Katsuhiko Mikoshiba, Karin Pernet-Gallay, Andrea Volterra
Cell, published online September 24, 2025 DOI 10.1016/j.cell.2025.08.036 - Comorbidities in the mouse model of temporal lobe epilepsy induced by intrahippocampal kainate.
Samalens L, Beets C, Courivaud C, Kahane P, Depaulis A.
Epilepsia. 2025 Jul 17. doi: 10.1111/epi.18553. Online ahead of print. - Subcortical correlates of consciousness with human single neuron recordings
Michael Pereira, Nathan Faivre, Fosco Bernasconi, Nicholas Brandmeir , Jacob E Suffridge, Kaylee Tran, Shuo Wang , Victor Finomore, Peter Konrad , Ali Rezai, Olaf Blanke
Elife. 2025 May 22:13:RP95272. doi: 10.7554/eLife.95272. - The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules.
Dharshini Gopal, Juliette Wu, Julie Delaroche, Christophe Bosc, Manon De Andrade, Eric Denarier, Gregory Effantin, Annie Andrieux, Sylvie Gory-Fauré, Laurence Serre & Isabelle Arnal
Nature Communications, 2025, 16 (1), pp.6210. (10.1038/s41467-025-61679-0) - Relaxometry and contrast-free cerebral microvascular quantification using balanced steady-state free precession MR fingerprinting.
Coudert T, Delphin A, Barrier A, Legris L, Warnking JM, Lamalle L, Doneva M, Lemasson B, Barbier EL, Christen T.
Magn Reson Med. 2025 Jul;94(1):302-316. doi: 10.1002/mrm.30434. Epub 2025 Jan 17.