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Grenoble Institut des Neurosciences

Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective. Verry C, Dufort S, Lemasson B, Grand S, Pietras J, Troprès I, Crémillieux Y, Lux F, Mériaux S, Larrat B, Balosso J, Le Duc G, Barbier EL, Tillement O. Sci Adv.. 2020 Jul 15;6(29):eaay5279. doi: 10.1126/sciadv.aay5279. eCollection 2020 Jul. PMID: 32832613 Free PMC article

Targeting the cholinergic anti-inflammatory pathway with vagus nerve stimulation in patients with Covid-19? Bonaz B, Sinniger V, Pelissier S. Bioelectron Med.. 2020 Jul 29;6:15. doi: 10.1186/s42234-020-00051-7. eCollection 2020. PMID: 32743022

Huntington's disease alters human neurodevelopment. Barnat M, Capizzi M, Aparicio E, Boluda S, Wennagel D, Kacher R, Kassem R, Lenoir S, Agasse F, Braz BY, Liu JP, Ighil J, Tessier A, Zeitlin SO, Duyckaerts C, Dommergues M, Durr A, Humbert S. Science. 2020 Jul 16:eaax3338. doi: 10.1126/science.aax3338. Online ahead of print. PMID: 32675289

Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. Agasse F, Mendez-David I, Christaller W, Carpentier R, Braz BY, David DJ, Saudou F, Humbert S. Cell Rep. 2020 Jul 7;32(1):107865. doi: 10.1016/j.celrep.2020.107865. PMID: 32640230

A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder. Li N, Baldermann JC, Kibleur A, Treu S, Akram H, Elias GJB, Boutet A, Lozano AM, Al-Fatly B, Strange B, Barcia JA, Zrinzo L, Joyce E, Chabardes S, Visser-Vandewalle V, Polosan M, Kuhn J, Kühn AA, Horn A. Nat Commun. 2020 Jul 3;11(1):3364. doi: 10.1038/s41467-020-16734-3. PMID: 32620886

Dementia and subthalamic deep brain stimulation in Parkinson disease: A long-term overview. Bove F, Fraix V, Cavallieri F, Schmitt E, Lhommée E, Bichon A, Meoni S, Pélissier P, Kistner A, Chevrier E, Ardouin C, Limousin P, Krack P, Benabid AL, Chabardès S, Seigneuret E, Castrioto A, Moro E. Neurology. 2020 Jul 28;95(4):e384-e392. doi: 10.1212/WNL.0000000000009822. Epub 2020 Jul 1. PMID: 32611633

Functional connectivity is preserved but reorganized across several anesthetic regimes. Becq GJC, Habet T, Collomb N, Faucher M, Delon-Martin C, Coizet V, Achard S, Barbier EL. Neuroimage. 2020 Jun 1;219:116945. doi: 10.1016/j.neuroimage.2020.116945. PMID: 32497787

Mapping the insula with stereo-electroencephalography: The emergence of semiology in insula lobe seizures. Singh R, Principe A, Tadel F, Hoffmann D, Chabardes S, Minotti L, David O, Kahane P. Ann Neurol. 2020 Jun 15. doi: 10.1002/ana.25817. PMID: 32542728

Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin. Bruyère J, Abada YS, Vitet H, Fontaine G, Deloulme JC, Cès A, Denarier E, Pernet-Gallay K, Andrieux A, Humbert S, Potier MC, Delatour B, Saudou F. Elife. 2020 May 26;9:e56371. doi: 10.7554/eLife.56371. PMID: 32452382

Autologous Mesenchymal Stem Cells Improve Motor Recovery in Subacute Ischemic Stroke: a Randomized Clinical Trial. Jaillard A, Hommel M, Moisan A, Zeffiro TA, Favre-Wiki IM, Barbieux-Guillot M, Vadot W, Marcel S, Lamalle L, Grand S, Detante O; (for the ISIS-HERMES Study Group). Transl Stroke Res. 2020 May 27. doi: 10.1007/s12975-020-00787-z. PMID: 32462427

Traffic signaling: new functions of huntingtin and axonal transport in neurological disease. Vitet H, Brandt V, Saudou F. Curr Opin Neurobiol. 2020 May 11;63:122-130. doi: 10.1016/j.conb.2020.04.001. Online ahead of print. PMID: 32408142
Effect of Abeta oligomers on neuronal APP triggers a vicious cycle leading to the propagation of synaptic plasticity alterations to healthy neurons. Rolland M, Powell R, Jacquier-Sarlin M, Boisseau S, Reynaud-Dulaurier R, Martinez-Hernandez J, André L, Borel E, Buisson A, Lanté F. J Neurosci. 2020 May 22:JN-RM-2501-19. doi: 10.1523/JNEUROSCI.2501-19.2020. PMID: 32444385

Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome. Reynaud-Dulaurier R, Benegiamo G, Marrocco E, Al-Tannir R, Surace EM, Auwerx J, Decressac M. Brain. 2020 Jun 1;143(6):1686-1696. doi: 10.1093/brain/awaa105. PMID: 32413099

Four core properties of the human brain valuation system demonstrated in intracranial signals. Lopez-Persem A, Bastin J, Petton M, Abitbol R, Lehongre K, Adam C, Navarro V, Rheims S, Kahane P, Domenech P, Pessiglione M. Nature Neurosci. 2020 May;23(5):664-675. doi: 10.1038/s41593-020-0615-9. Epub 2020 Apr 13. PMID: 32284605

MAP6 is an intraluminal protein that induces neuronal microtubules to coil. Cuveillier C, Delaroche J, Seggio M, Gory-Fauré S, Bosc C, Denarier E, Bacia M, Schoehn G, Mohrbach H, Kuli? I, Andrieux A, Arnal I, Delphin C. Science Adv. 2020 Apr 1;6(14):eaaz4344. doi: 10.1126/sciadv.aaz4344. PMID: 32270043